Prognostic Value of Functional Parameters of ¹⁸F-FDG-PET Images in Patients with Primary Renal/Adrenal Lymphoma

Table 3

Univariate and multivariate Cox regression analyses of factors associated with OS.

Variables		Median OS (month)	Univariate analysis		Multivariate analysis
			HR (95% CI)		HR (95% CI)
Age (year)	<50	20.63		0.745
	≥50	17.55
Gender	Male	17.00		0.347
	Female	22.00
Location	Kidney	14.00		0.432
	Adrenal gland	17.50
	Kidney + adrenal gland	20.00
Ann Arbor stage	I∼III	27.44	11.150 (1.220–101.924)	0.033
	IV	11.10
Subtype/origin	B cell	21.62		0.244
	T cell	2.00
	NK cell	15.00
^18F-FDG-PET parameters
SUVmax	<7.37	25.20		0.264
	≥7.37	16.57
SUVmean	<7.00	23.25		0.575
	≥7.00	15.64
MTV	<88.80	21.13	5.044 (0.983–25.882)	0.052
	≥88.80	10.25
TLG	<13.05	31.00		0.065
	≥13.05	15.60
Texture features
GLCM_Correlation	<0.695	22.38	5.089 (0.911–28.421)	0.064
	≥0.695	11.17
GLRLM_HGRE	<171.95	28.13		0.076
	≥171.95	12.09
GLRLM_SRHGE	<163.2	28.13		0.076
	≥163.2	12.09
GLRLM_LRHGE	<215.8	28.13		0.076
	≥215.8	12.09
GLRLM_RLNU	<216.6	25.00	9.016 (1.041–78.112)	0.046	9.016 (1.041–78.112)	0.046
	≥216.6	10.38
GLZLM_HGZE	<205.05	28.13		0.076
	≥205.05	12.09
GLZLM_GLNU	<2.9	30.43	9.366 (1.096–80.051)	0.041
	≥2.9	12.08
GLZLM_ZLNU	<9.75	28.13		0.076
	≥9.75	12.09
HISTO_Entropy	<12.6	28.13		0.076
	≥12.6	12.09
GLCM_Entropy	<71.14	27.22	5.639 (1.051–30.244)	0.044
	≥71.14	11.30

^∗p < 0.05.