Early Achilles Enthesis Involvement in a Murine Model of Spondyloarthropathy: Morphological Imaging with Ultrashort Echo-Time Sequences and Ultrasmall Superparamagnetic Iron Oxide (USPIO) Particle Evaluation in Macrophagic Detection

<div>Sagittal RARE T2 Fat-Sat sequence (a) and 3D-UTE PD-w acquisition sequence (b) with focus on normal enthesis area (in vivo) for morphologic assessment. The anterior part of the enthesis looks brighter than the posterior part in in vivo assessment in UTE sequences (b) but not in RARE T2 Fat-Sat acquisition sequences (a) at D0. Correlation with histology in the same normal rat in MT (c). Red star: enthesis in a preinsertional tendon; yellow arrow: sesamoido-fibrocartilage; white arrow: periosto-fibrocartilage; red arrow: entheso-fibrocartilage; blue arrow: fibrous enthesis in a normal Achilles tendon. MT: Masson’s trichroma; PD-w: proton density weighted images.</div>

Contrast Media & Molecular Imaging

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Figure 1: Early Achilles Enthesis Involvement in a Murine Model of Spondyloarthropathy: Morphological Imaging with Ultrashort Echo-Time Sequences and Ultrasmall Superparamagnetic Iron Oxide (USPIO) Particle Evaluation in Macrophagic Detection 

Figure 1 | Early Achilles Enthesis Involvement in a Murine Model of Spondyloarthropathy: Morphological Imaging with Ultrashort Echo-Time Sequences and Ultrasmall Superparamagnetic Iron Oxide (USPIO) Particle Evaluation in Macrophagic Detection 