Research Article
An Efficient T1 Contrast Agent for Labeling and Tracking Human Embryonic Stem Cells on MRI
Figure 1
Schematic of synthesis of compound 2 (MnEtP). Reagents and conditions: step 1: (1) BF
3OEt
2, 1 h DCM 25°C; (2) DDQ, 2.5 h 10%; step 2: (1) MnCl
2·4H
2O, DMF, reflux 5 h; (2) 25°C, 16 h 85% [
13,
16].
