An Efficient T₁ Contrast Agent for Labeling and Tracking Human Embryonic Stem Cells on MRI

Table 1

Quantification of intracellular Mn content by ICP-AES.

Incubation conditions	Retention period (h)	[Mn] (fg/cell)
Control	No labeling	BDL
10 μM, 24 h	0	12.5
10 μM, 24 h	24	2
10 μM, 24 h	48	BDL
10 μM, 24 h	72	BDL
40 μM, 30 min	0	37
40 μM, 30 min	24	7
40 μM, 30 min	48	BDL
40 μM, 30 min	72	BDL

Cell retention results up to 72 h postlabeling for optimized labeling conditions are shown (BDL: below detection limit).