Porous Silicon as a Platform for Radiation Theranostics Together with a Novel RIB-Based Radiolanthanoid

Figure 6

Combined histological and autoradiographic data from two example tumors. (a) Photographed histological section stained with hematoxylin and eosin, together with a microscope image of the relevant region produced with a tenfold magnification. The dark areas in the microscope image present the injected [¹⁵⁹Dy]THCPSi particles. (b) Corresponding autoradiographic image produced to the neighboring unstained section together with the outline of the section. The gross properties of the activity is presented with a 50 µm resolution and the detailed properties in the magnified region with a 2 µm resolution. Both images were obtained from the same measurement. (c) Combined information of (a) and (b). The upper row presents a tumor with the [¹⁵⁹Dy]THCPSi particles present close to the surface and the bottom row a tumor with the particles closer to the center.

(a)

(b)

(c)