Research Article

Gallium-68-Labelled Indocyanine Green as a Potential Liver Reserve Imaging Agent

Table 1

Biodistribution of 68Ga-NOTA-ICG in percentage of injected dose per gram of organ at 15 min, 30 min, 45 min, 60 min, 2 h and 3 h postinjection in normal rats .

Organ/tissuePercentage of injected dose per gram of organ
15 min30 min45 min60 min2 h3 h

Blood0.68 ± 0.120.48 ± 0.160.32 ± 0.210.26 ± 0.110.19 ± 0.130.11 ± 0.07
Liver0.54 ± 0.260.41 ± 0.230.36 ± 0.190.33 ± 0.130.27 ± 0.110.14 ± 0.06
Kidney2.81 ± 1.121.92 ± 1.061.36 ± 0.471.24 ± 0.360.91 ± 0.430.57 ± 0.37
Intestine0.12 ± 0.060.30 ± 0.160.34 ± 0.130.37 ± 0.111.87 ± 0.961.46 ± 0.83
Bone0.16 ± 0.060.14 ± 0.030.13 ± 0.050.11 ± 0.030.14 ± 0.040.11 ± 0.02
Muscle0.11 ± 0.070.12 ± 0.050.10 ± 0.040.12 ± 0.060.09 ± 0.030.05 ± 0.03
Lung0.15 ± 0.080.10 ± 0.020.08 ± 0.030.07 ± 0.040.05 ± 0.020.03 ± 0.01
Brain0.07 ± 0.030.05 ± 0.020.04 ± 0.020.05 ± 0.010.04 ± 0.030.04 ± 0.02
Stomach0.08 ± 0.040.06 ± 0.030.09 ± 0.030.09 ± 0.040.07 ± 0.030.06 ± 0.02
Gallbladder0.27 ± 0.160.48 ± 0.190.42 ± 0.180.31 ± 0.130.34 ± 0.120.33 ± 0.13
Liver/blood0.790.851.131.271.421.27

Values are the mean ± standard deviation .