Toward the Optimization of (+)-[<sup>11</sup>C]PHNO Synthesis: Time Reduction and Process Validation

<div>Chromatogram of semipreparative HPLC of full synthesis at room temperature (a), route A synthesis without TEA and LAH (b), route E without LAH (c), and route F in which the reaction is quenched after Grignard reaction (d).</div>

Contrast Media & Molecular Imaging

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Figure 8

Figure 8: Toward the Optimization of (+)-[<sup>11</sup>C]PHNO Synthesis: Time Reduction and Process Validation 

Contrast Media & Molecular Imaging

Toward the Optimization of (+)-[11C]PHNO Synthesis: Time Reduction and Process Validation

Figure 8

Toward the Optimization of (+)-[¹¹C]PHNO Synthesis: Time Reduction and Process Validation