In Vivo Detection and Measurement of Aortic Aneurysm and Dissection in Mouse Models Using Microcomputed Tomography with Contrast Agent

<div>(a) Time course of contrast enhancement within the aorta of the three healthy C57BL/6 mice after a single tail vein injection of 100 <i>μ</i>l ExiTron nano 12000 per 25 g mouse. (b) Mean CT number (HU) at the second hour after a single tail vein injection of ExiTron nano 12000 at a dose of 75<i>μ</i>l/25g, 100<i>μ</i>l/25g, and 150<i>μ</i>l/25 g per mouse, respectively. Mean CT number was measured by placing a region of interest within the aorta.</div>

Contrast Media & Molecular Imaging

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Figure 2: In Vivo Detection and Measurement of Aortic Aneurysm and Dissection in Mouse Models Using Microcomputed Tomography with Contrast Agent 