Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer’s Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [⁶⁸Ga]Ga-TC3-OGDOTA

Table 1

Summary of the animal use.

	Condition/genotype	Sex	Mice injected with [^68Ga]Ga-TC3-OGDOTA	Subset used				Mice used for TTC staining	Total number of mice
				PET	Thin sections	CLARITY	Unused
Stroke model	MCAO	m	8	5	4	3	1	2	10
	Sham-operated controls	m	6	3	3	3	0	—	6
AD model	5xFAD	m	3	3	0	3	0	—	3
		f	7	7	0	3	0	—	7
	WT controls	m	3	3	0	1	0	—	3
		f	6	6	0	1	0	—	6

Died during anaesthesia.