Research Article

Differentiation of Pituitary Adenoma from Rathke Cleft Cyst: Combining MR Image Features with Texture Features

Table 2

Differences of qualitative MR image features between pituitary adenoma and Rathke cleft cyst in the training group.

Qualitative MR image featuresPituitary adenoma, N (%) (n = 68)Rathke cleft cyst, N (%) (n = 40) value (<0.01)

Flow voids
 Presence3 (4)2 (5)0.866
 Absence65 (96)38 (95)(Fisher’s exact tests)
Signal intensity on the contrast-enhanced images
 Hypointense or isointense3 (4)30 (75)<0.001
 Hyperintense65 (96)10 (25)(chi-square tests)
Heterogeneity on the contrast-enhanced images
 Homogenous34 (50)25 (62.5)0.208
 Heterogeneous34 (50)15 (37.5)(chi-square tests)
Signal intensity on T2WI
 Hypointense or isointense35 (64)14 (40)0.028
 Hyperintense20 (36)21 (60)(chi-square tests)
Heterogeneity on T2WI
 Homogenous27 (49)20 (57)0.456
 Heterogeneous28 (51)15 (43)(chi-square tests)

MR, magnetic resonance; T2WI, T2-weighted image. Correction adjusted level of significance .