Research Article

Differentiation of Pituitary Adenoma from Rathke Cleft Cyst: Combining MR Image Features with Texture Features

Table 3

Differences of texture features between pituitary adenoma and Rathke cleft cyst on the contrast-enhanced image and T2WI based on the Mann–Whitney U test.

Texture feature, mean (range)Contrast-enhanced imageT2WI
Pituitary adenomaRathke cleft cystPituitary adenomaRathke cleft cyst

Histo
 Energy0.05 (0.02∼0.14)0.07 (0.03∼0.13)<0.0010.05 (0.03∼0.13)0.05 (0.02∼0.14)0.263
 Entropy1.42 (1.00∼1.75)1.33 (1.07∼1.59)0.0021.40 (1.11∼1.62)1.45 (1.07∼1.68)0.078
 Kurtosis4.93 (1.70∼41.27)8.82 (2.91∼21.31)<0.0016.07 (1.59∼28.98)5.40 (1.51∼20.23)0.599
 Skewness0.25 (−1.19∼4.67)1.25 (−1.72∼3.23)<0.0010.27 (−2.87∼3.34)−0.43 (−3.37∼1.56)0.004

GLCM
 Correlation0.58 (0.27∼0.85)0.44 (0.09∼0.82)<0.0010.52 (0.11∼0.89)0.45 (−0.34∼0.86)0.173
 Contrast41.01 (6.64∼161.70)43.19 (4.54∼154.60)0.60049.76 (11.81∼146.29)84.69 (9.40∼717.59)0.028
 Dissimilarity4.31 (1.66∼9.10)3.98 (1.39∼8.74)0.3104.60 (2.25∼8.63)5.64 (1.852∼22.209)0.108
 Energy0.01 (0.00∼0.03)0.01 (0.00∼0.04)<0.0010.01 (0.00∼0.03)0.01 (0.00∼0.03)0.566
 Entropy2.60 (1.76∼3.08)2.34 (1.87∼2.85)<0.0012.60 (1.91∼3.00)2.52 (1.85∼2.98)0.579
 Homogeneity0.30 (0.21∼0.54)0.40 (0.25∼0.57)0.0010.30 (0.22∼0.51)0.34 (0.16∼0.53)0.984

T2WI, T2-weighted image; Histo, histogram-based matrix; GLCM, grey-level co-occurrence matrix.