Iodine-Enhanced Micro-CT Imaging of Soft Tissue on the Example of Peripheral Nerve Regeneration

Figure 11

Comparison of μCT with histology work-up of a regenerating peripheral nerve in a silk fibroin conduit (∗): (a) maximum intensity projection showing the 3D context of perfused blood vessel (i) and regenerated axons (iii); (b) inverted minimum intensity projection visualizes bridging of the defect by a blood vessel without perfusion with the contrast agent (ii); (c) position of the histological slide can be found in μCT due to landmark structures, such as blood vessels contrast agent-perfused blood vessels (i), blood vessels without contrast agent (ii), and myelinated axons (iii) can be identified in histology and μCT; (d) arrows i, ii, and iii indicate the used landmark structure of the regenerated tissues.

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