Highly Biocompatible Nanoparticles of Au@Fluorescent Polymers as Novel Contrast Agent for In Vivo Bimodality NIR Fluorescence/CT Imaging

<div>Computed tomography (CT) images of Au@FP nanoparticles and clinical CT contrast agent (Ultravist® 300) of increasing concentration (<i>μ</i>g/mL) (a); standard curve of CT values (hounsfield units, HU) of Au@FP nanoparticles at different concentrations (b); confocal images of HUVECs incubated with 200 <i>μ</i>g/mL of Au@FP nanoparticles for 2 h the nuclei of cells were stained by DAPI (A), tubulin structure was stained by Alexa Fluor® 488-labeled antibody (B), the images of Au@FP nanoparticles in cells (C), and the merged images (D). Scale bars are 25 <i>μ</i>m.</div>

Contrast Media & Molecular Imaging

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Figure 2: Highly Biocompatible Nanoparticles of Au@Fluorescent Polymers as Novel Contrast Agent for In Vivo Bimodality NIR Fluorescence/CT Imaging 