Biodistribution of [¹¹C]-Metformin and mRNA Expression of Placentae Metformin Transporters in the Pregnant Chinchilla

Figure 2

Whole-body [¹¹C]-metformin PET scans were performed after i.v. tracer injection. (a) Attenuation corrected maximum intensity projection of [¹¹C]-metformin biodistribution in a chinchilla 30 min after injection demonstrates uptake in submandibular glands, liver, kidneys, intestine, and urinary bladder (indicated by arrows). Transaxial slices of [¹¹C]-metformin biodistribution on merged PET/CT images (arrows indicate metformin avid organs) are displayed in (b) submandibular glands, (c) thorax, (d) liver, and (e) kidneys.