Research Article

Diagnostic Accuracy of Machine Learning-Based Radiomics in Grading Gliomas: Systematic Review and Meta-Analysis

Table 3

Summary of the results evaluated in the reviewed studies.

Study and yearMethodAlgorithmDataset/HGG-LGGMRI sequenceBest performanceLimitation
AUCDA (%)Sen (%)Spe (%)

Cho et al. 2018Classic machine learningMultiple algorithmsWHO II–IV (n = 285)/210-75T1, T1-C, T2, T2- FLAIR0.9492.9297.8679.11No dataset separation information for training and testing cohort. Sample imbalance size between LGG and HGG.

Tian et al. 2018Classic machine learningSVMWHO II–IV gliomas (n = 153)/111-42Multiparametric0.9996.8096.4097.30Sample imbalance sample size between LGG and HGG.

Hashido et al. 2018Classic machine learningLogistic regressionWHO II–IV (n = 46)/31-15ASL, PWI (DSC)0.96NA89.3092.90Small sample size. Small sample size used in the training set. Large feature number than the total sample size.

Vamvakas et al. 2019Classic machine learningSVMWHO I–IV (n = 40) 20-20Multiparametric0.9695.509596Small sample size.

Zhao et al. 2020Classic machine learningRFWHO II-III gliomas (n = 36) 17-19T1-C, T2- FLAIR0.8678.1078.3077.80Small sample size. Large feature number compared to the total sample size.