^99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans

Table 1

Average total number of disintegrations (N) of ^99mTc-CXCR4-L in source organs calculated from six healthy volunteers (3 females and 3 males).

Target organ	N (mean ± SD) (MBq·h/MBq)
	Females	Males
Breasts	(1.39 ± 0.30) E − 01
Gallbladder content	(3.07 ± 1.30) E − 02	(1.33 ± 0.09) E − 02
LLI content	(6.46 ± 1.27) E − 02	(7.27 ± 0.40) E − 02
SI content	(1.01 ± 0.20) E − 01	(1.14 ± 0.06) E − 01
ULI content	(1.32 ± 0.26) E − 01	(1.48 ± 0.08) E − 01
Heart content	(2.96 ± 0.18) E − 02	(3.68 ± 0.75) E − 02
Kidneys	(1.01 ± 0.20) E − 01	(1.46 ± 0.20) E − 01
Liver	(1.23 ± 0.41) E − 01	(1.66 ± 0.25) E − 01
Lungs	(1.70 ± 0.38) E − 01	(2.41 ± 0.40) E − 01
Testes		(2.53 ± 0.09) E − 02
Urinary bladder	(2.48 ± 0.40) E − 01	(1.70 ± 0.45) E − 01
Remainder of the body	1.13 ± 0.08	1.83 ± 0.04