Review Article

MnDPDP: Contrast Agent for Imaging and Protection of Viable Tissue

Figure 9

MnDPDP: myocardial Mn2+ uptake in healthy human volunteers [18]. MnDPDP 5 μmol/kg was administered i.v. inside magnet with infusion time of 5 min (n = 5) or 30 min (n = 5). R1 values obtained at 1.5 T over 40 min after start of infusion were converted to tissue [Mn2+] in arbitrary units (a.u.). ΔR1 values were as follows: 5 min, 0.32 s−1; 30 min, 0.35 s−1 (reproduced with permission from J Magn Reson Imaging).