Research Article

Distinguishing Lymphomatous and Cancerous Lymph Nodes in 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography by Radiomics Analysis

Table 1

Patient characteristics.

Number of patients (%)Number of lymph nodes (%)

All patients324492
Sex
Men201 (62.04)317 (64.43)
Women123 (37.96)175 (35.57)

Patients with lymphoma (%)Patients with cancer (%)

Number of patients26262
Age (mean ± SD)48.51 (19.09)55.19 (12.81)
Stage^
I14 (5.34)2 (3.23)
II139 (53.05)26 (41.94)
III73 (27.86)23 (37.1)
IV36 (13.74)11 (17.74)

Number of lymph nodes (%)

Histologic findingsLymphoma373Cancer119
DLBCL124 (33.24)Gastric cancer40 (33.61)
HL116 (31.1)Esophageal cancer20 (16.81)
NKT24 (6.43)Nasopharyngeal carcinoma20 (16.81)
FL22 (5.9)Liver cancer13 (10.92)
MCL13 (3.49)Lung cancer10 (8.4)
T-LBL7 (1.88)Pancreatic cancer6 (5.04)
AITL7 (1.88)Gallbladder cancer3 (2.52)
PTCL NOS6 (1.61)Breast cancer2 (1.68)
MALT6 (1.61)Sarcoma2 (1.68)
ALK4 (1.07)Laryngeal cancer2 (1.68)
Burkitt2 (0.54)Thyroid cancer1 (0.84)
Nonspecific43 (11.53)

Abbreviations: DLBCL, diffuse large B-cell lymphoma; HL, Hodgkin’s lymphoma; FL, follicular lymphoma; MCL, mantle cell lymphoma; T-LBL, T-lymphoblastic lymphoma; AITL, angioimmunoblastic T-cell lymphoma; PTCL NOS, peripheral T cell lymphoma, not otherwise specified; MALT, mucosa-associated lymphoid tissue lymphoma; ALK, ALK-positive anaplastic large cell lymphoma; Burkitt, Burkitt lymphoma. Part of patients has adopted clinical staging criteria because they have not undergone further diagnosis and treatment in our hospital. This part of the patients did not get the most detailed pathological classification from the pathological examination, even if immunohistochemical staining or gene sequencing was performed, which included the following (1) can only be judged as non-Hodgkin’s lymphoma and the specific type cannot be determined (35 cases); (2) can only be judged as small B-cell lymphoma and cannot be further classified (5 cases), difficult to judge as diffuse large B-cell lymphoma or mantle-cell lymphoma (2 cases); (3) can only be judged as B-cell lymphoma, but cannot be further distinguished (1 case).