Application of Distributed Parameter Model to Assessment of Glioma IDH Mutation Status by Dynamic Contrast-Enhanced Magnetic Resonance Imaging

<div>A 54-year-old male with IDH-mutant glioblastoma in the right front lobe. (a) FLAIR, showing a mass of slight hyperintensity with surrounding high signal edema in the right front lobe; (b) contrast-enhanced T<sub>1</sub>WI, showing a heterogeneous contrast-enhanced mass with irregular shape; (c) histopathological image of hematoxylin-eosin stain (x10); (d) permeability-surface area product PS (mL/min/100 mL); (e) fractional volume of the intravascular space <i>Vp</i> (mL/100 mL); (f) fractional volume of the extravascular extracellular space <i>Ve</i> (mL/100 mL) by the distributed parameter model.</div>

Contrast Media & Molecular Imaging

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Figure 1

Figure 1: Application of Distributed Parameter Model to Assessment of Glioma IDH Mutation Status by Dynamic Contrast-Enhanced Magnetic Resonance Imaging 

Figure 1 | Application of Distributed Parameter Model to Assessment of Glioma IDH Mutation Status by Dynamic Contrast-Enhanced Magnetic Resonance Imaging 