Review Article

18F-PSMA-1007 PET in Biochemical Recurrent Prostate Cancer: An Updated Meta-Analysis

Table 2

Technical aspects of 18F-PSMA-1007 PET/CT or PET/MRI in the included studies.

AuthorsHybrid imaging modality (scanner)Radiotracer injected activityTime interval (in minutes) between radiotracer injection and image acquisitionImage analysisVerification of PET findingsOther imaging performed for comparison

Ahmadi Bidakhvidi et al. [22]PET/CT (GE Discovery MI-4 or Siemens Biograph TruePoint)3 MBq/kg81 ± 16VisualNR

Dietlein et al. [23]PET/CT (Siemens Biograph mCT 128 Flow)343 ± 49 MBq120VisualHistology or follow-up68Ga-PSMA-11, 18F-DCFPyL or 18F-JK-PSMA-7 PET/CT

Giesel et al. [24]PET/CT (Siemens Biograph mCT Flow)251.5 (154-326) MBq63 ± 6 and 180 ± 5Visual and semiquantitative (SUV)NR

Giesel et al. [25]PET/CT (Siemens Biograph mCT/mCT20 or mCT Flow)301 ± 46 MBq92 ± 26VisualNR

Liu et al. [26]PET/MRI (Siemens Biograph mMR)263 (164–353) MBq60VisualNR

Morawitz et al. [27]PET/CT (Siemens Biograph mCT 128)229 ± 27 MBq120VisualHistology or follow-upCT

Rahbar et al. [28]PET/CT (Siemens mCT)4 MBq/kg
336.7 ± 46 MBq
60 and 120Visual and semiquantitative (SUV)NR

Rahbar et al. [29]PET/CT (Siemens mCT)4 MBq/kg
338 ± 44.31 MBq
120Visual and semiquantitative (SUV)NR

Rauscher et al. [30]PET/CT (Siemens Biograph mCT)325 ± 40 MBq94 ± 22Visual and semiquantitative (SUV)Histology or follow-up68Ga-PSMA-11 PET/CT

Sachpekidis et al. [31]PET/CT (Siemens Biograph mCT 128 S)237 (131–266) MBqDynamic part from 0 to 60 and static part at 70Visual, semiquantitative (SUV) and quantitativeNR

Sprute et al. [32]PET/CT (Siemens Biograph mCT/mCT Flow or GE Discovery 710)270 (106-356) MBq90 (47–169)VisualHistology

Watabe et al. [33]PET/CT (GE Discovery 710)259 ± 37 MBq57.7 ± 4.9VisualHistology or follow-up

Witkowska-Patena et al. [34]PET/CT (GE Discovery 710)296 ± 14 MBq95 ± 12Visual and semiquantitative (SUV)NR18F-choline PET/CT

Witkowska-Patena et al. [35]PET/CT (GE Discovery 710)295.5 ± 14.1 MBq95 ± 12Visual and semiquantitative (SUV)Histology or follow-up

Wondergem et al. [36]PET/CT (Siemens Biograph‐16 TruePoint)324 (239–363) MBq90VisualHistology or follow-up18F‐DCFPyL PET/CT

CT = computed tomography; MBq = MegaBecquerel; MRI = magnetic resonance imaging; NR = not reported; PET = positron emission tomography; SUV = maximal standardized uptake value.