Research Article

Multiparameter Analysis Using 18F-FDG PET/CT in the Differential Diagnosis of Pancreatic Cystic Neoplasms

Table 1

The differences in baseline characteristics and PET/CT parameters between serous cystic neoplasm (SCN) and mucinous cystic neoplasm (MCN) patients.

Serous cystic neoplasms (n = 27)Mucinous cystic neoplasms (n = 14)

Baseline characteristics
Age (years)56.67 ± 12.2443.50 ± 13.27
Female sex, n (%)20 (74.07%)12 (85.71%)
Diameter (cm)3.97 ± 1.884.34 ± 1.87

Conventional metabolic parameters of PET/CT
SUVmax1.82 ± 0.501.75 ± 0.860.763
SUVmean1.33 ± 0.430.99 ± 0.330.014
MTV49.03 ± 59.5958.50 ± 49.540.613
TLG61.52 ± 79.2964.01 ± 74.970.923

Advanced metabolic parameters of PET/CT
SURmax (T/P)1.43 ± 0.801.42 ± 1.090.980
SURmean (T/P)1.13 ± 0.480.99 ± 0.670.449
MTV (T/P)14.23 ± 19.8413.79 ± 17.510.945
TLG (T/P)19.22 ± 30.5321.31 ± 40.670.854
SURmax (T/A)1.15 ± 0.571.39 ± 1.230.596
SURmean (T/A)0.92 ± 0.330.96 ± 0.790.214
MTV (T/A)18.22 ± 27.4613.21 ± 14.020.527
TLG (T/A)20.54 ± 37.2018.19 ± 30.830.841

Texture parameters of PET/CT
SD0.29 ± 0.120.40 ± 0.290.194
Median1.33 ± 0.450.94 ± 0.330.006
Percentile 5th0.88 ± 0.380.47 ± 0.230.001
Percentile 95th1.82 ± 0.501.75 ± 0.860.763
Skewness0.21 ± 0.570.78 ± 0.450.002
Kurtosis0.01 ± 0.850.69 ± 1.960.124
Diffentropy0.26 ± 0.160.26 ± 0.160.903
Diffvariance0.04 ± 0.040.05 ± 0.040.801
Contrast0.07 ± 0.060.08 ± 0.070.507
Entropy0.36 ± 0.300.42 ± 0.330.549

SUV : standardized uptake value; MTV : metabolic tissue volume; TLG : total lesion glycolysis; SUR: standardized uptake ratio; T/P : tumor/normal pancreas; T/A : tumor/aorta; SD : standard deviation.