Diagnostic Performance of ¹⁸F-FDG PET(CT) in Bone-Bone Marrow Involvement in Pediatric Neuroblastoma: A Systemic Review and Meta-Analysis

Table 2

Subgroup analyses.

Characteristic (studies)	Sensitivity (95% CI)	Specificity (95% CI)	LR+ (95% CI)	LR− (95% CI)	DOR (95% CI)	AUC
Analysis
LBA (2)	0.89 (0.81–0.94)	0.78 (0.70–0.85)	8.67 (0.57–130.98)	0.15 (0.09–0.27)	43.78 (7.74–247.59)	NA
PBA (5)	0.78 (0.64–0.88)	0.90 (0.79–0.97)	5.25 (1.91–14.44)	0.18 (0.03–1.07)	43.33 (10.12–185.47)	0.94
Scan model
PET (2)	0.90 (0.76–0.97)	1.00 (0.90–1.00)	31.82 (4.60–220.10)	0.11 (0.02–0.77)	348.28 (31.97–3794.50)	0.50
PET/CT (5)	0.83 (0.75–0.89)	0.77 (0.69–0.84)	3.38 (2.54–4.51)	0.22 (0.05–0.99)	26.61 (12.31–57.54)	0.90