Diagnostic Accuracy of 18F-FDG-PET/CT and MRI in Predicting the Tumor Response in Locally Advanced Cervical Carcinoma Treated by Chemoradiotherapy: A Meta-Analysis

Table 3

Patients’ pathologic and imaging characteristics.

Author

FIGO stage

Histopathology

Pelvic LN metastasis

Prevalence of distant metastasis

3-OS

DFI (month)

MTV

TLG

Persistence

CR

PFS

SUVmean

IB

IIA-IIB

IIIA-IIIB

SCC

Adenocarcinoma

Partial response

Complete response

Rufini et al.

3 (3.4%)

72 (81.7%)

13 (14.7%)

77 (87.5%)

11 (12.5%)

40 (45.5%)

10 (11.4%)

N/A

15.5

33.8 (1.2–180.0)

240.2 (7.9–2417.0)

N/A

N/A

N/A

2.1 (1.1–5.7)

1.8 ± 0.7

Cetina et al.

2/16 (12%)

8/16 (50%)

3/16 (19%)

15/16-(94%)

1 (6.2%)

N/A

N/A

N/A

14.5

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Perrone et al.

N/A

N/A

N/A

32 (80%)

8 (20%)

17 (42.5%)

1 (2.5%)

88%

N/A

N/A

N/A

8 (20%)

33 (82.5%)

78%

7.5 ± 5.1

N/A

Chen et al.

37 (26%)

78 (55%)

27 (19%)

114 (80%)

28 (20%)

61 (43%)

27 (19%)

N/A

N/A

28.1 ± 42.7

216.1 ± 280.5

22 (15%)

120 (84%)

N/A

5.12 ± 1.17

1.28

Choi et al.

3 (1.9%)

102 (75%)

17 (12.4%)

124 (91.2%)

9 (6.6%)

N/A

12 (22.2%)

N/A

N/A

N/A

N/A

18 (13.2%)

124 (91%)

N/A

5.7 ± 2.6

2.5 ± 0.8

Oh et al.

3 (5%)

46 (77%)

8 (13%)

52 (87%)

8 (13%)

42 (70%)

6 (10%)

93.6%

N/A

N/A

N/A

4 (7%)

43 (73%)

71.9%

N/A

N/A

SCC: squamous cell carcinoma; LN: lymph node; DFI: disease-free interval; 3-OS: 3-month overall survival; MTV: metabolic tumor volume; TLG: total lesion glycolysis; CR: complete response; PFS: progression-free survival; and SUV: standardized uptake value.