Effect of Different MPTP Administration Intervals on Mouse Models of Parkinson’s Disease

Figure 1

Effects of different modes of MPTP administration on motor function and anxiety behavior in mice. (a) Chemical structure of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). (b) Behavior trajectory diagram of mice in the open-field test: red is the mouse activity outer frame line and green is the center grid, B represented start position, and E represented the end of recording the mouse position. The open-field test was utilized to check the total movement distance (c) and the total rest time (d) of the mice in each group. (e) Pole test was applied to determine the motor function of mice in each group. ∗∗P < 0.01 vs. control group.

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