Research Article
Prognostic Value of Intratumor Metabolic Heterogeneity Parameters on 18F-FDG PET/CT for Patients with Colorectal Cancer
Table 2
Comparison of clinicopathological and PET parameters between recurrence and no recurrence in 129 patients with curative radical surgery.
| | Variables | Recurrence (–) | Recurrence (+) | value |
| | Gender (male/female) | 63/37 | 20/9 | 0.555 | | Age (median) | 65 | 61 | 0.106 | | Location | | Right colon | 33 | 8 | | | Left colon | 28 | 9 | | | Rectum | 39 | 12 | 0.856 | | Pathological type | | Adenocarcinoma | 86 | 21 | | | MAC/SRC | 14 | 8 | 0.087 | | Degree of differentiation | | Low | 22 | 10 | | | Median | 72 | 18 | | | High | 6 | 1 | 0.368 | | Measured tumor length (cm) (mean ± SD) | 4.86 ± 1.77 | 5.52 ± 1.70 | 0.075 | | T stage | | T1-2 | 29 | 5 | | | T3-4 | 71 | 24 | 0.206 | | Regional lymph nodes | | N– | 37 | 10 | | | N+ | 63 | 19 | 0.804 | | Nerve invasion | | Negative | 87 | 23 | | | Positive | 13 | 6 | 0.304 | | Tumor thrombus | | Negative | 87 | 16 | | | Positive | 13 | 13 | ＜0.001 | | Stage, AJCC | | I | 22 | 3 | | | II | 41 | 4 | | | III | 37 | 22 | 0.001 | | CEA (ng/ml) (median) | 3.81 | 6.04 | 0.105 | | CA19-9 (U/ml) (median) | 13.66 | 16.77 | 0.259 | | SUVmax (median) | 15.37 | 14.40 | 0.348 | | SUVpeak (median) | 10.67 | 10.81 | 0.552 | | SUVmean (median) | 9.00 | 7.99 | 0.204 | | MTV (ml) (median) | 10.28 | 12.87 | 0.003 | | TLG (g) (median) | 97.55 | 135.16 | 0.073 | | HI-1 (median) | 0.23 | 0.22 | 0.032 | | HI-2 (median) | 8.29 | 17.74 | 0.001 |
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MAC, mucinous adenocarcinoma; SRC, signet ring cell carcinoma; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; SUV, standardized uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis; HI, heterogeneity index. Bold values, P < 0.05.
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