Clinical Efficacy of Chinese and Western Medicine in the Treatment of Benign Thyroid Nodules: A Meta-Analysis

Table 1

Basic characteristics of the literature reporting on benign thyroid nodules included for this meta-analysis.

Study	Year	Sample time (year.month)	Cases treat/con	Age (years)		Sex (male/female)		Follow-up time	Study design	Outcome measures
				Treat group	Con group	Treat group	Con group
Jiang Hongyu	2004	2002.05–2003.05	43/30	39.9 ± 14.3	40.4 ± 16.3	16/27	7/23	3	RCT	(1)(2)
Fu Lijuan	2020	2018.10–2019.10	78/78	65.4 ± 21.6	10.7 ± 7.3	38/40	39/39	6	RCT	(1)
Liu Yong	2021	2019.01–2019.12	42/42	65.4 ± 21.6	65.4 ± 21.7	23/19	24/18	6	RCT	(1)(3)
Wang Leilei	2014	2010.07–2012.12	95/90	51.4 ± 8.2	50.9 ± 8.5	21/74	19/71	6	RCT	(1)(2)(3)
Wang Junlin	2021	2018.10–2019.10	78/78	31–86	31–86	38/40	39/39	6	RCT	(1)(4)(5)(6)(7)
Lin Min	2020	2019.01–2019.06	30/30	NR	NR	NR	NR	3	RCT	(1)(2)(4)(5)(6)
Mou Linan	2017	2014.10–2015.10	30/30	43.1 ± 4.9	42.9 ± 4.1	10/20	11/19	2	RCT	(2)(4)(5)(6)(7)
Tong Rui	2020	2018.02–2019.02	52/52	41.5 ± 7.4	43.8 ± 7.2	11/41	13/39	6	RCT	(1)(2)(3)(4)(5)(6)(7)
Shen Yuguo	2018	2014.06–2016.06	62/63	29–54	29–54	20/42	20/43	6	RCT	(1)(2)(3)(4)(5)(6)
Liu Wenxiu	2019	2015.02–2018.02	74/71	47.1 ± 10.7	46.5 ± 11.4	24/50	22/49	6	RCT	(1)
Qiu Jintao	2020	2017.06–2019.10	30/30	41.3 ± 10.8	42.4 ± 9.7	6/24	4/26	6	RCT	(1)(3)
Zhang Lili	2018	2017.01–2017.09	68/68	42.2 ± 5.9	42.6 ± 5.4	23/45	24/44	6	RCT	(1)(2)(7)

Note. Treat: treatment; con: control; RCT: randomized controlled trial; NR: not reported; (1) effective rate; (2) maximum nodule diameter; (3) thyroid volume (TV); (4) free triiodothyronine (FT3); (5) free thyroxine (FT4); (6) thyroid-stimulating hormone (TSH); (7) traditional Chinese medicine syndrome score.