Regulation of the Proliferation of Diabetic Vascular Endothelial Cells by Degrading Endothelial Cell Functional Genes with QKI-7

Figure 3

QKI-7 with high-glucose treatment inhibited the expression of CD144, NLGN1, and TSG6 in endothelial cells and promoted cell proliferation.  < 0.05, with the untreated group as the control. Treated endothelial cells induced by differentiation of human pluripotent stem cells with 50 mM high concentration glucose, and detection of the expression levels of CD144, NLGN1, and TSG6 by RT-qPCR (a) and western blot (b). CCK-8 was used to evaluate the changes in cell proliferation efficiency of the high-glycemic treatment group and the untreated group (c).

(a)

(b)

(c)