Long Noncoding RNA CASC2 Facilitated Wound Healing through miRNA-155/HIF-1α in Diabetic Foot Ulcers

Figure 4

Overexpression of miR-155 abrogated the function of lncRNA CASC2. (a) Relative expression of lncRNA CASC2 was detected by RT-qPCR. (b, c), Flow cytometry to evaluate the apoptosis of fibroblasts. (d) The proliferation activity of the cell was measured by MTT. (e) Healing of wound assay to determine the ability of cells migration at 0 h and 24 h. (f) Western blot measurement of HIF-1α, VEGF, and Col-I protein expression levels in fibroblasts. and vs. group of DFU, , , and against a group of DFU + CASC2.

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