Genetic Polymorphism of E2F1 Influences Susceptibility to Ovarian Cancer in a Chinese Population

Table 2

Comparison of genotype and allele frequency between the ovarian cancer group and the control group

E2F1 polymorphism	Control group (N = 130)		Ovarian cancer group (N = 80)		OR(95%CI)^a
	n	Percentage	n	Percentage
rs3213172
CC	64	49.2	28	35.0	1.00^REF
CT	52	40.0	45	56.2	1.98(1.09–3.59)	0.024
TT	14	10.8	7	8.8	1.14(0.42–3.14)	0.795
C	180	69.2	101	63.1	1.00^REF
T	80	30.8	59	36.9	1.31(0.87–1.99)	0.197
rs3213173
CC	58	44.6	30	37.5	1.00^REF
CT	52	40.0	37	46.3	1.38(0.75–2.53)	0.305
TT	20	15.4	13	16.2	1.26(0.55–2.87)	0.587
C	168	64.6	97	60.6	1.00^REF
T	92	35.4	63	39.1	1.19(0.79–1.78)	0.411
rs3213176
GG	65	50.0	37	46.3	1.00^REF
GA	51	39.2	30	37.5	1.03(0.56–1.89)	0.411
AA	14	10.8	13	16.2	1.63(0.69–3.84)	0.260
G	181	69.6	104	65.0	1.00^REF
A	79	30.4	56	35.0	1.23(0.81–1.88)	0.325

OR, odds ratio; CI, confidential index; adjusted for sex and age by logistic regression model.