Intraperitoneal Delivery of Iopamidol to Assess Extracellular pH of Orthotopic Pancreatic Tumor Model by CEST-MRI

<div><i>In vivo</i> CT data showing the uptake of iopamidol over time into KPC961 orthotopic tumors following the IV + infusion protocol. (a) Delta Hounsfield units (<i>Δ</i>HU) was obtained by subtracting the mean intensity from the tumor ROI in each postcontrast CT image (5–25 min) from the mean intensity of the tumor ROI in the precontrast CT image; (b) CT images showing an axial view and the tumor ROI in red, before and 25 min postiopamidol administration using the IV + infusion protocol. Hounsfield units (HU).</div>

Contrast Media & Molecular Imaging

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Figure 2

Figure 2: Intraperitoneal Delivery of Iopamidol to Assess Extracellular pH of Orthotopic Pancreatic Tumor Model by CEST-MRI 