Intraperitoneal Delivery of Iopamidol to Assess Extracellular pH of Orthotopic Pancreatic Tumor Model by CEST-MRI

<div>Clearance of iopamidol in KPC961 orthotopic tumors following IP injection protocol. (a) Delta Hounsfield units (<i>Δ</i>HU) were obtained by subtracting the mean intensity from the tumor ROI in each postcontrast CT image (20, 40 min, 24, and 48 hr) from the mean intensity of the tumor ROI in the precontrast CT image; (b) representative CT images showing tumor ROI in red and axial view for the precontrast, axial, and coronal views for the 40 min postcontrast, and axial views for 24 and 48 hr postcontrast CT images. Hounsfield units (HU).</div>

Contrast Media & Molecular Imaging

fig4

Figure 4

Figure 4: Intraperitoneal Delivery of Iopamidol to Assess Extracellular pH of Orthotopic Pancreatic Tumor Model by CEST-MRI 