Ultrasound-Based Three-Dimensional Microangiography for Repeated Noninvasive Imaging of Neovascularization

Figure 4

Neovascularization evaluated with ultrasound-based angiographies: (a) a series of processed cine image from one axolotl in each group. A lookup table (fire) was applied to highlight flow velocity differences; (b) plot illustrating the mean vessel volume fraction over time measured by high-frequency ultrasound. ANOVA showed that time is the only significant factor, hence a total of all groups were calculated. Blue: mean vessel volume fraction from all subjects. Error bars for total: Bonferroni corrected 95%-confidence intervals. Red: mean vessel volume fraction sham. Orange: mean vessel volume fraction CSCI. Green: mean vessel volume fraction TSCI. Small red, orange, and green points are individual data points. White arrowheads pointing at spinal cord blood vessels. White circles represent the SCI sites. Cranial side is to the right.

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