Contrast Media & Molecular Imaging

In Vivo Imaging of Inflammation and Infection


Status
Published

Lead Editor

1University of Turku, Turku, Finland

2Åbo Akademi University, Turku, Finland

3University of Bologna, Bologna, Italy

4University of Wisconsin-Madison, Madison, USA

5Charité Universitätsmedizin, Berlin, Germany


In Vivo Imaging of Inflammation and Infection

Description

Inflammation is a significant component of several chronic diseases involving the cardiovascular, metabolic, respiratory, gastrointestinal, musculoskeletal, and nervous systems. Timely identification and localization of inflammatory foci are critical for adequate treatment of patients. Conventional imaging techniques (computed tomography, magnetic resonance imaging, and ultrasound) may detect such pathology but mainly rely on anatomical changes and are not fully capable of discriminating active inflammatory pathology from the anatomical changes resulting from prior successful therapy or surgery. In addition, inflammatory foci cannot be detected in the early phase of development because of the lack of substantial anatomical changes at this time.

Nuclear imaging with radiotracers that accumulate at the site of inflammation has become an established tool in the evaluation of several inflammatory and infectious conditions. They can reveal molecular and cellular changes and provide sensitive detection of even small inflammatory and/or infectious foci at an early stage of disease.

This special issue would focus on the recent advances of different techniques used for imaging of inflammation and infection; provide an outline and examples of their clinical use in evaluation of inflammatory/infectious conditions; and discuss some of the emerging techniques that are currently being developed for imaging of inflammation/infection. This issue accepts original research articles as well as review articles. It will provide a multidisciplinary forum that will discuss pros and cons of established methods and probes in different clinical applications and show new developments in this area.

Potential topics include but are not limited to the following:

  • Methods for imaging of inflammation and infection
    • Nuclear imaging
    • Computed tomography
    • Magnetic resonance imaging
    • Ultrasound
    • Multimodal and hybrid imaging (PET/MRI; SPECT/MRI)
  • Clinical conditions for imaging of inflammation and infection
    • Suspected systemic and local infections
    • Vasculitis
    • Sarcoidosis
    • Inflammatory bowel diseases
    • Arthritis
    • Other applications
  • Emerging protocols for imaging of inflammation and infection
    • New imaging probes (chemistry and preclinical studies)

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 3817871
  • - Editorial

In Vivo Imaging of Inflammation and Infection

Anne Roivainen | Xiang-Guo Li | ... | Sarah Ohrndorf
  • Special Issue
  • - Volume 2018
  • - Article ID 9892604
  • - Research Article

A Comparative 68Ga-Citrate and 68Ga-Chloride PET/CT Imaging of Staphylococcus aureus Osteomyelitis in the Rat Tibia

Petteri Lankinen | Tommi Noponen | ... | Anne Roivainen
  • Special Issue
  • - Volume 2018
  • - Article ID 8092781
  • - Research Article

Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate

Durga M. S. H. Chandrupatla | Gerrit Jansen | ... | Conny J. van der Laken
  • Special Issue
  • - Volume 2018
  • - Article ID 9713691
  • - Review Article

Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

Irina Velikyan
  • Special Issue
  • - Volume 2017
  • - Article ID 7645070
  • - Research Article

Comparison of 68Ga-DOTA-Siglec-9 and 18F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry

Helena Virtanen | Johanna M. U. Silvola | ... | Anne Roivainen
  • Special Issue
  • - Volume 2017
  • - Article ID 6975841
  • - Review Article

In Vivo PET Imaging of Adenosine 2A Receptors in Neuroinflammatory and Neurodegenerative Disease

Anna Vuorimaa | Eero Rissanen | Laura Airas
  • Special Issue
  • - Volume 2017
  • - Article ID 9548478
  • - Research Article

Integrating a 19F MRI Tracer Agent into the Clinical Scale Manufacturing of a T-Cell Immunotherapy

Charles F. O’Hanlon | Tamara Fedczyna | ... | Brooke M. Helfer
  • Special Issue
  • - Volume 2017
  • - Article ID 3179607
  • - Clinical Study

Head-to-Head Comparison of 68Ga-Citrate and 18F-FDG PET/CT for Detection of Infectious Foci in Patients with Staphylococcus aureus Bacteraemia

Soile P. Salomäki | Jukka Kemppainen | ... | Anne Roivainen
  • Special Issue
  • - Volume 2017
  • - Article ID 9754293
  • - Research Article

Intensity of 18F-FDG PET Uptake in Culture-Negative and Culture-Positive Cases of Chronic Osteomyelitis

Petteri Lankinen | Marko Seppänen | ... | Hannu T. Aro
  • Special Issue
  • - Volume 2017
  • - Article ID 9256858
  • - Research Article

Kinetic Modelling of Infection Tracers [18F]FDG, [68Ga]Ga-Citrate, [11C]Methionine, and [11C]Donepezil in a Porcine Osteomyelitis Model

Lars Jødal | Svend B. Jensen | ... | Søren B. Hansen
Contrast Media & Molecular Imaging
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Acceptance rate58%
Submission to final decision65 days
Acceptance to publication40 days
CiteScore3.200
Impact Factor1.984
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