Contrast Media & Molecular Imaging

Imaging Biomarkers in Translational Small Animal Models


Publishing date
01 Jan 2019
Status
Published
Submission deadline
31 Aug 2018

Lead Editor

1University of Santiago de Compostela, Santiago de Compostela, Spain

2Hospital Clínico Santiago de Compostela, Santiago de Compostela, Spain

3University of Leeds, Leeds, UK

4Sapienza University of Rome, Rome, Italy


Imaging Biomarkers in Translational Small Animal Models

Description

Preclinical molecular imaging has become an essential tool in translational research with animal models of multiple human diseases. The great interest achieved lies in the fact that current clinical imaging techniques such as PET, SPECT, CT, and MRI are also available for use in preclinical models, providing similar image quality despite using animals as small as mice and rats. Thus, the same quantitative molecular imaging biomarkers can be proposed to be used from very early preclinical research with animals to clinical trials in patients. Nevertheless, the use of preclinical molecular imaging is still reduced due to the lack of efficient and standardized methods for extracting accurate imaging biomarkers for each particular disease model. The current challenges in translational molecular imaging are to define appropriate molecular imaging biomarkers for each disease that can be used for the follow-up of new treatments from the small animal model to the patient.

The main focus of this special issue will be on recent advances in molecular imaging biomarkers in small animal models. In particular, we take an interest in manuscripts that report biomarkers derived from preclinical imaging that can be directly transferred to clinical trials such as those biomarkers derived from PET, SPECT, CT, and MRI. This special issue accepts original research articles as well as review articles describing the state of the art about a particular disease model.

Potential topics include but are not limited to the following:

  • Imaging biomarkers for neurodegenerative diseases models
  • Biomarkers in preclinical cancer imaging
  • Imaging of inflammation and infection biomarkers
  • Imaging biomarkers for cardiovascular diseases
  • Endocrinology and metabolism imaging biomarkers

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 9469041
  • - Editorial

Imaging Biomarkers in Translational Small Animal Models

Pablo Aguiar | Anxo Fernández-Ferreiro | ... | Charalampos Tsoumpas
  • Special Issue
  • - Volume 2019
  • - Article ID 3128529
  • - Review Article

Preclinical Imaging Biomarkers for Postischaemic Neurovascular Remodelling

Richa Gandhi | Charalampos Tsoumpas
  • Special Issue
  • - Volume 2019
  • - Article ID 3438093
  • - Research Article

Hybrid PET/MR Kernelised Expectation Maximisation Reconstruction for Improved Image-Derived Estimation of the Input Function from the Aorta of Rabbits

Daniel Deidda | Nicolas A. Karakatsanis | ... | Charalampos Tsoumpas
  • Special Issue
  • - Volume 2018
  • - Article ID 4580919
  • - Research Article

Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice

Jessica Buck | James R. Larkin | ... | Nicola R. Sibson
  • Special Issue
  • - Volume 2018
  • - Article ID 5906471
  • - Research Article

Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy

Noémi Kovács | Krisztián Szigeti | ... | Domokos Máthé
  • Special Issue
  • - Volume 2018
  • - Article ID 3727109
  • - Research Article

Image-Guided Neutron Capture Therapy Using the Gd-DO3A-BTA Complex as a New Combinatorial Treatment Approach

Ki-Hye Jung | Ji-Ae Park | ... | Yongmin Chang
  • Special Issue
  • - Volume 2018
  • - Article ID 3526438
  • - Research Article

Quantification of Nanoparticle Enhancement in Polarized Breast Tumor Macrophage Deposits by Spatial Analysis of MRI and Histological Iron Contrast Using Computer Vision

Avigdor Leftin | Jason A. Koutcher
  • Special Issue
  • - Volume 2018
  • - Article ID 4608186
  • - Review Article

How to Modulate Tumor Hypoxia for Preclinical In Vivo Imaging Research

Sven De Bruycker | Christel Vangestel | ... | Sigrid Stroobants
  • Special Issue
  • - Volume 2018
  • - Article ID 8382148
  • - Research Article

MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management

Miguel Ángel Morcillo | Ángel García de Lucas | ... | Jorge Martínez-Torrecuadrada
  • Special Issue
  • - Volume 2018
  • - Article ID 8751267
  • - Research Article

Early Imaging Biomarker of Myocardial Glucose Adaptations in High-Fat-Diet-Induced Insulin Resistance Model by Using 18F-FDG PET and [U-13C]glucose Nuclear Magnetic Resonance Tracer

Yi-Hsiu Chung | Kuan-Ying Lu | ... | Gigin Lin
Contrast Media & Molecular Imaging
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Acceptance rate58%
Submission to final decision65 days
Acceptance to publication40 days
CiteScore4.000
Journal Citation Indicator0.610
Impact Factor3.161
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