X. Guan, R. A. Segal, M. Shearer, T. B. Martonen, "Mathematical Model of Airflow in the Lungs of Children II: Effects of Ventilatory Parameters", Computational and Mathematical Methods in Medicine, vol. 3, Article ID 290916, 12 pages, 2000. https://doi.org/10.1080/10273660008833064
Mathematical Model of Airflow in the Lungs of Children II: Effects of Ventilatory Parameters
In an effort to develop more effective aerosol therapy procedures, we examined airflow patterns in the lung of a child (age four years). In particular, we were concerned with how ventilatory parameters (i.e., breathing rate and tidal volume) affected the patterns of airflow around tumors. To conduct the study, a computational fluid dynamics package, FIDAP was used to define a model lung. The results of simulations show the extent to which changing ventilatory parameters can affect flow patterns in the neighborhood of the tumors as well as drug distribution throughout the lung.
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