185845.fig.003a
(a)
185845.fig.003b
(b)
185845.fig.003c
(c)
185845.fig.003d
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185845.fig.003e
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185845.fig.003f
(f)
Figure 3: Mean UCP-2 and TRPv4 scores for human and rat liver. In rat liver ((a) and (b) manual scores; mean ± s.e.m., ) and in human liver ((c) and (d); ±s.e.m., ). (e) and (f) show area fraction (%) UCP-2 and TRPv4 of immunostaining measured on automated histomorphometry in rat liver (mean and 95% CI, ). Pairwise -tests showed that the increases seen in central zones compared to either mid- or peri-portal zones on manual scoring in both rat and human liver were highly significant (), confirmed by significant reductions in % immunostaining in rat liver in mid and portal as compared to central zones on one-way ANOVA ( for UCP-2 and  .001 for TRPv4).