Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles

<table>The O<sub>2</sub> concentrations (normalized by <svg height="10.925" id="M58" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 15.375 10.925" width="15.375" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.925)">
<g transform="translate(72,-63.26)">
<text transform="matrix(1,0,0,-1,-71.95,66.44)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑐</tspan>
</text>
<text transform="matrix(1,0,0,-1,-66.76,63.31)">
<tspan style="font-size: 8.75px; " x="0" y="0">𝑃</tspan>
</text>
</g>
</g>
</svg>) in a follicle of 1 mm radius when (a) the COC rests on the inner boundary of the follicle wall and (b) the COC is a distance of one radius (<svg height="11.05" id="M59" style="vertical-align:-3.24037pt" version="1.1" viewbox="0 0 15.3375 11.05" width="15.3375" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.05)">
<g transform="translate(72,-63.16)">
<text transform="matrix(1,0,0,-1,-71.95,66.44)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑟</tspan>
</text>
<text transform="matrix(1,0,0,-1,-66.85,63.31)">
<tspan style="font-size: 8.75px; " x="0" y="0">𝐶</tspan>
</text>
</g>
</g>
</svg>) away from the follicle wall. Explicit inclusion of the COC in the model shows a decrease in O<sub>2</sub> concentration within the antrum in the vicinity of the COC.</table>

Computational and Mathematical Methods in Medicine

fig3

Figure 3

Figure 3: Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles 