Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles

Table 1

Nominal model parameters and sensitivity analysis. The sensitivity analysis is carried out by considering the nominal parameter values as the baseline (with the COC centrally located within the follicle) and calculating the change in the mean O₂ concentration at the COC boundary (𝑟_𝐶) for a 10% increase or decrease in each parameter from the baseline.

Parameter	Value	Reference	+10%	−10%
α G	0.3 (no units)	[14, 15]	−1.5%	+1.4%
CP	0.128 (mol m^−3)	[14]	+41%	−41%
DA	2.5 × 10^−9 (m^2 s^−1)	[28]	+25%	−30%
DG	2.5 × 10^−9 (m^2 s^−1)	[28]	+3.1%	−3.7%
hP	0.1 (m s^−1)	Variable (see text)	See discussion	See discussion
qG	0.0363 (mol m^−3s^−1)	[14]	−3.1%	+3.1%
𝑞COC	1.62 × 10^−6 (mol m^−2s^−1)	From [44], units converted using 𝑟𝐶	−28%	+28%
rF	1 × 10^−3 (m)	See text	+1.9%	−4.5%
rC	160 × 10^−6 (m)	[45]	+30%	−37%
vG	1.14 × 10^−15 (m^3)	[15]	−6.9%	+6.2%
a	43.1 × 10^6	[15]	−6.9%	+6.2%
b	281.6	[15]	+5.6%	−7.6%
c	−387.3	[15]	−5.4%	+4.6%