Computational Modeling of Tumor Response to Vascular-Targeting Therapies—Part I: Validation

Table 2

Dosing Schedule for Simulated Drugs.

Drug	Dosing Schedule	Therapeutic Levels?
AI	Once every two weeks	Maintained between successive treatments due to 20 day half-life of drug [43]
Cytotoxic Chemotherapeutic	Daily (up to 6 weeks in a row)	Maintained between successive treatments due to 1.8 hour half life of drug [44]
VDA	Once every three weeks	Maintained only in a 24 hour window after drug administration due to 4.2 hour half-life of drug [45]