Simulation of Arrhythmogenic Effect of Rogue RyRs in Failing Heart by Using a Coupled Model
Figure 4
Occurrence of DAD following three action potentials in failing myocyte when = 1.0 rogue RyR/m2. Five figures from top to bottom represent membrane potential, cytoplasmic , SR luminal [Ca2+]SR, , and line-scan image along longitudinal direction of the cell, respectively, in failing ventricular myocyte.
