Computational and Mathematical Methods in Medicine

Research Article

A General Latent Class Model for Performance Evaluation of Diagnostic Tests in the Absence of a Gold Standard: An Application to Chagas Disease

Table 7

Prevalence rates of Chagas’ disease in each of the three strata according to each level of the three covariates obtained with model ModII .


Prevalence
Stratum	Covariates	Mean	P2.5%	P97.5%

I	General	0.6215	0.5516	0.6915
	AGE 30 years	0.4975	0.3723	0.6237
	AGE > 30 years	0.7298	0.6277	0.8136
	GEN-male	0.5169	0.3899	0.6380
	GEN-female	0.7138	0.6006	0.8054
	RFE-no	0.4527	0.3238	0.5729
	RFE-yes	0.7634	0.6619	0.8471

II	General	0.1277	0.0512	0.2633
	AGE 30 years	0.0909	0.0310	0.2022
	AGE > 30 years	0.1811	0.0693	0.3700
	GEN-male	0.0845	0.0276	0.2035
	GEN-female	0.1935	0.0705	0.3837
	RFE-no	0.0895	0.0292	0.1987
	RFE-yes	0.1839	0.0718	0.3770

P2.5%: 2.5th percentile; P97.5%: 97.5th percentile; vth Stratum: I, II (donors with negative or positive serology and inconclusive in the screening test, resp.,); AGE-age (≤30, >30 years); GEN-gender (male, female); RFE-presence of at least two of three risk factors epidemiological (origin from an endemic region, contact with the vector transmitting the disease, and family history of Chagas’ disease).