Computational and Mathematical Methods in Medicine / 2012 / Article / Tab 6

Research Article

Identification and Functional Annotation of Genome-Wide ER-Regulated Genes in Breast Cancer Based on ChIP-Seq Data

Table 6

KEGG pathways enriched with the nearest-neighbor genes of ER binding sites ( -value < 0.01).

KEGG IDPathways name -valueNumber of genesNumber of different expressed genes

hsa05200Pathways in cancer 2216
hsa04510Focal adhesion0.00021514
hsa04360Axon guidance0.0009118
hsa04810Regulation of actin cytoskeleton0.00121411
hsa04010MAPK signaling pathway0.00221512
hsa04114Oocyte meiosis0.002498
hsa04144Endocytosis0.00241211
hsa04115p53 signaling pathway0.002477
hsa05216Thyroid cancer0.002454
hsa05218Melanoma0.003373
hsa04020Calcium signaling pathway0.004114
hsa04062Chemokine signaling pathway0.0064119
hsa04914Progesterone-mediated oocyte maturation0.008577
hsa01100Metabolic pathways0.00863528
hsa00450Selenoamino acid metabolism0.008843
hsa05414Dilated cardiomyopathy0.009677
hsa03440Homologous recombination0.009743