Research Article
Fast Parameters Estimation in Medication Efficacy Assessment Model for Heart Failure Treatment
Table 3
Comparison of hemodynamic parameters by simulation and clinical observation.
| | | Baseline value | Simulated value | Measured value |
| | Enalapril 20 mg/d | | | | | SBP (mmHg) | 155* | 143 | 137* | | DBP (mmHg) | 101* | 92 | 88* | | MAP (mmHg) | 119 | 109 | | | PP (mmHg) | 54 | 51 | | | HR (beat/min) | 73 | 73 | | | CO (L/min) | 5.26 | 5.48 | | | SV (mL) | 72 | 75 | | | EF (%) | 28.35 | 32.05 | | | SW (J/beat) | 2.95 | 2.70 | | | CII | 9.85 | 4.01 | |
| | Lisinopril 20 mg/d | | | | | SBP (mmHg) | 158+ | 141 | 140+ | | DBP (mmHg) | 94+ | 90 | 88+ | | MAP (mmHg) | 115 | 107 | | | PP (mmHg) | 64 | 51 | | | HR (beat/min) | 73 | 73 | | | CO (L/min) | 5.11 | 5.62 | | | SV (mL) | 70 | 77 | | | EF (%) | 27.24 | 34.53 | | | SW (J/beat) | 3.03 | 2.48 | | | CII | 13.22 | 1.80 | |
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Data acquired from the literature [20]. +Data acquired from the literature [21]. The rest data are estimated by models.
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