Computational and Mathematical Methods in Medicine / 2012 / Article / Fig 2

Research Article

How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

Figure 2

The virtual experiments are conducted priming at day zero and later after a certain time interval. In this case the boost has been performed after about ten weeks. While the antibodies are produced by plasma cells derived by expanding clones of B cells, the injected antigen is cleared and immunocomplexes are formed. The secondary immune response to the boost is stronger and faster than the response to the priming because of the immunological memory (not shown).

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