A Mathematical Model of Immune-System-Melanoma Competition
Figure 2
System behavior obtained with the use of different vaccination protocols: untreated (blue dashed line), activated OT1 CTLs (red dot-dashed lines), Anti-CD137 monoclonal antibodies (green dotted lines), and activated OT1 CTLs + Anti-CD137 monoclonal antibodies (black solid lines). From left to right, top to bottom: melanoma cells (), tumor antigens (), activated OT1 CTLs in the skin (), naïve CTLs (), antibodies in the skin (), antibodies in the injection point (, and activated OT1 CTLs in the injection point ().