Research Article

A Mathematical Model of Immune-System-Melanoma Competition

Figure 2

System behavior obtained with the use of different vaccination protocols: untreated (blue dashed line), activated OT1 CTLs (red dot-dashed lines), Anti-CD137 monoclonal antibodies (green dotted lines), and activated OT1 CTLs + Anti-CD137 monoclonal antibodies (black solid lines). From left to right, top to bottom: melanoma cells ( ), tumor antigens ( ), activated OT1 CTLs in the skin ( ), naïve CTLs ( ), antibodies in the skin ( ), antibodies in the injection point ( , and activated OT1 CTLs in the injection point ( ).
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