Survival Data Analysis with Time-Dependent Covariates Using Generalized Additive Models

Table 5

Test of significance for spline effects.

Spline effect	Δ	d.f.
Age	0.0039 (Model IV-II)	0.005
Prothrombin time	12.15 (Model VI-IV)	3.45
Bilirubin	22.97 (Model V-IV)	3.01