Space Constrained Homology Modelling: The Paradigm of the RNA-Dependent RNA Polymerase of Dengue (Type II) Virus

<table>The Dengue polymerase model produced by the 3D space-aided approach (colour turquoise) superposed to the Dengue type II X-ray crystal structure (coloured red, PDB entry: 2BMF). All major <i>Flaviviridae </i>polymerase motifs have been structurally conserved in the Dengue polymerase model. </table>

Computational and Mathematical Methods in Medicine

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Figure 4

Figure 4: Space Constrained Homology Modelling: The Paradigm of the RNA-Dependent RNA Polymerase of Dengue (Type II) Virus 