Space Constrained Homology Modelling: The Paradigm of the RNA-Dependent RNA Polymerase of Dengue (Type II) Virus

<table>Surface comparison of the crystal structures of the HCV, BVDV, and Dengue RdRp (PDB entry: 2BMF) versus the 3D model of the Dengue polymerase that was produced by the 3D space-aided homology modelling approach. The surfaces are colored according to their electrostatic potential.</table>

Computational and Mathematical Methods in Medicine

fig6

Figure 6

Figure 6: Space Constrained Homology Modelling: The Paradigm of the RNA-Dependent RNA Polymerase of Dengue (Type II) Virus 