An Improved Computer Vision Method for White Blood Cells Detection

<table>Detection numerical example: (a) the image used as an example, (b) segmented image, (c) edge map, (d) initial particles <svg height="15.8375" id="M147" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 17.799999 15.8375" width="17.799999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.775)"><path d="M613 208h28l-40 -208h-585v25q54 6 71 21t17 55v479q0 38 -18 53t-70 18v25h577v-201h-25q-16 100 -66 133q-47 34 -171 34q-38 0 -51.5 -12t-13.5 -42v-225q82 2 117 32q36 31 45 117h26v-338h-26q-7 88 -43 121q-35 34 -119 34v-242q0 -32 17.5 -44t65.5 -12
q117 0 182 54q24 20 41 45.5t41 77.5z" id="x1D404"></path></g>
<g transform="matrix(.012,-0,0,-.012,11.4,7.613)"><path d="M241 635q53 0 94 -28.5t63.5 -76t33.5 -102.5t11 -116q0 -58 -11 -112.5t-34 -103.5t-63.5 -78.5t-94.5 -29.5t-95 28t-64.5 75t-34.5 102.5t-11 118.5q0 58 11.5 112.5t34.5 103t64.5 78t95.5 29.5zM238 602q-32 0 -55.5 -25t-35.5 -68t-17.5 -91t-5.5 -105
q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g>
</svg>, (e) trial elements <b>T</b> produced by the DE operators, (f) new population <svg height="15.8375" id="M148" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 17.799999 15.8375" width="17.799999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.775)"><path d="M613 208h28l-40 -208h-585v25q54 6 71 21t17 55v479q0 38 -18 53t-70 18v25h577v-201h-25q-16 100 -66 133q-47 34 -171 34q-38 0 -51.5 -12t-13.5 -42v-225q82 2 117 32q36 31 45 117h26v-338h-26q-7 88 -43 121q-35 34 -119 34v-242q0 -32 17.5 -44t65.5 -12
q117 0 182 54q24 20 41 45.5t41 77.5z" id="x1D404"></path></g>
<g transform="matrix(.012,-0,0,-.012,11.4,7.613)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g>
</svg>, (g) trial elements produced considering <svg height="15.8375" id="M149" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 17.799999 15.8375" width="17.799999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.775)"><path d="M613 208h28l-40 -208h-585v25q54 6 71 21t17 55v479q0 38 -18 53t-70 18v25h577v-201h-25q-16 100 -66 133q-47 34 -171 34q-38 0 -51.5 -12t-13.5 -42v-225q82 2 117 32q36 31 45 117h26v-338h-26q-7 88 -43 121q-35 34 -119 34v-242q0 -32 17.5 -44t65.5 -12
q117 0 182 54q24 20 41 45.5t41 77.5z" id="x1D404"></path></g>
<g transform="matrix(.012,-0,0,-.012,11.4,7.613)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g>
</svg> as input population, (h) new population <svg height="15.8375" id="M150" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 17.799999 15.8375" width="17.799999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.775)"><path d="M613 208h28l-40 -208h-585v25q54 6 71 21t17 55v479q0 38 -18 53t-70 18v25h577v-201h-25q-16 100 -66 133q-47 34 -171 34q-38 0 -51.5 -12t-13.5 -42v-225q82 2 117 32q36 31 45 117h26v-338h-26q-7 88 -43 121q-35 34 -119 34v-242q0 -32 17.5 -44t65.5 -12
q117 0 182 54q24 20 41 45.5t41 77.5z" id="x1D404"></path></g>
<g transform="matrix(.012,-0,0,-.012,11.4,7.613)"><path d="M412 140l28 -9q0 -2 -35 -131h-373v23q112 112 161 170q59 70 92 127t33 115q0 63 -31 98t-86 35q-75 0 -137 -93l-22 20l57 81q55 59 135 59q69 0 118.5 -46.5t49.5 -122.5q0 -62 -29.5 -114t-102.5 -130l-141 -149h186q42 0 58.5 10.5t38.5 56.5z" id="x32"></path></g>
</svg>, and (i) final particle configuration after 25 iterations.</table>

Computational and Mathematical Methods in Medicine

An Improved Computer Vision Method for White Blood Cells Detection

Figure 7