Power Analysis of C-TDT for Small Sample Size Genome-Wide Association Studies by the Joint Use of Case-Parent Trios and Pairs

Table 3

Contribution of mother or father genotypes to 𝑁_{𝑀>𝐶or𝐹>𝐶}, 𝑁_{𝑀<𝐶or𝐹<𝐶}, and 𝑁_{𝑀=𝐶or𝐹=𝐶} terms in C-TDT statistic.

	Mother or father genotype	Offspring genotype	Frequency	𝑁𝑀>𝐶or𝐹>𝐶	𝑁𝑀<𝐶or𝐹<𝐶	𝑁𝑀=𝐶or𝐹=𝐶
1	AA	AA	2	0	0	1
2	AA	AB	2	1	0	0
3	AB	AA	2	0	1	0
4	AB	AB	4	0	0	1
5	AB	BB	2	1	0	0
6	BB	AB	2	0	1	0
7	BB	BB	2	0	0	1